Transition of pemphigus vulgaris into pemphigus foliaceus confirmed by antidesmoglein ELISA profile.
نویسندگان
چکیده
منابع مشابه
Frequency of shifts over time in the profile of antidesmoglein antibodies in pemphigus vulgaris.
T he clinical features of pemphigus vulgaris (PV) are related to the presence and profile of antidesmoglein 3 (anti-dsg3) and antidesmoglein 1 (anti-dsg1) antibodies. Anti-dsg3 is associated with mucosal PV; the concurrent presence of anti-dsg3 and antidsg1, with mucocutaneous disease; and anti-dsg1 alone, with pemphigus foliaceus (PF). Shifts over time in the pattern of anti-dsg antibodies fro...
متن کاملEvaluation of sensitivity and specificity of enzyme-linked immunosorbent assay (ELISA) for detecting antidesmoglein 1 and 3 in Thai patients with pemphigus vulgaris and foliaceus.
OBJECTIVE Pemphigus is an acquired autoimmune blistering skin diseases, of which pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are two major subtypes. A novel commercial enzyme-linked immunosorbent assay (ELISA) against Dsg1 and Dsg3 has been well established for diagnosis and prediction of disease activity in PF and PV. At present, the benefit of anti-Dsg 1 and anti-Dsg 3 IgG by ELISA i...
متن کاملParaneoplastic Pemphigus Presenting as Mild Cutaneous Features of Pemphigus Foliaceus and Lichenoid Stomatitis with Antidesmoglein 1 Antibodies
Herein, we report a case of paraneoplastic pemphigus with mild skin features of pemphigus foliaceus and lichenoid stomatitis associated with B-cell lymphoma. A 49-year-old man presented with scattered blisters and erosions on the trunk along with mucosal blisters and erosions. Skin biopsy showed subcorneal acantholytic bulla and oral mucosal biopsy demonstrated lichenoid dermatitis. Direct immu...
متن کاملThe use of ELISA in pemphigus
Pemphigus is a group of autoimmune blistering diseases. There had been abundant evidence that antibodies against components within the desmosomes were responsible for its pathogenesis. The major antigens in pemphigus vulgaris and pemphigus foliaceus are desmoglein 3 (130 kDa) and desmoglein 1 (160 kDa) respectively. They are glycoproteins belonging to the cadherin family and form part of the tr...
متن کامل[Juvenile pemphigus vulgaris].
BACKGROUND Pemphigus vulgaris is a rare autoimmune blistering disease seen only, rarely, in children. CASE-REPORT Two young girls, aged four and 15 years respectively, presented with oral and/or cutaneous blisters (case 2). The diagnosis of pemphigus vulgaris was confirmed by histology (suprabasal acantholysis) and immunopathological analysis (direct and indirect immunofluorescence, antidesmo...
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ورودعنوان ژورنال:
- International journal of dermatology
دوره 41 8 شماره
صفحات -
تاریخ انتشار 2002